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Mast and Basal Cells
Duration: 1:15:09
Immunology /
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Learning Objectives
Review of the cells involved in immune system.
Granulocytes (Basophils and eosinophils).
Difference between a basophil and a mast cell.
Recap of production of basophils.
Chemicals that cause increase in their production.
Structure of basophil/mast cells.
Primary functions of the contents in their granules.
Concept of allergin and antigen.
Genetic disposition to allergic reactions.
How IgE antibodies mediate anaphylaxis.
Role of cGMP in relese of histamine. The mechanism of action of histamine.
cAMP and its function in membrane stabilization of mast cells.
The mechanism of releases of preformed chemotactic factors in the acute phase.
Different lipid mediators of anaphylaxis reaction.
Role of leukotrienes in mediating the late phase anaphylaxis reaction.
Potential effect of leukotriene B4 in causing inflammation.
The slow-reacting substances involved in anaphylaxis.
Mechanism of an anaphylactoid reaction.
Various triggers for allergy.
Role of eosinophils in reducing allergic reaction and secondary harmful effects of eosinophils on the body.
Eosinophils: basic structure and properties.
Functions of eosinophils in helminthic infections and antibody-dependent cellular cytotoxicity (ADCC).
An overview mechanism of ADCC.
The possible role of eosinophils in asthma.
Consequences of activation of eosinophils in case of asthma.
Different inflammatory chemical mediators released from eosinophils.
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Instructor
Videos in this series
Immune System Function Part 1
Immune System Function Part 2 (Effector Cells)
Overview (Innate and Acquired Arm)
Overview (Immune Cells)
Neutrophils
Natural Killer (NK) Cells
Mast and Basal Cells
Macrophages
MHC I and MHC II Loading
T Cells (part 1)
T Cells (part 2)
T Cells Maturation and Selection
T Cell Receptors and Immunoglobulins
T Cell Functions
B Cell Functions
Immunoglobulins
Type 1 Hypersensitivity Reactions - Allergies (Urdu-Hindi)
Type II Hypersensitivity Reactions
Type III Hypersensitivity Reactions
Type IV Hypersensitivity Reactions
Complement System
Tumor Immunity
Immune Pathology
Immune Pharmacology
IVIg A High Level Overview
Multiple Sclerosis-Pathophysiology
Multiple Sclerosis-Clinical Aspects
Self Tolerance and Microbe Triggered Autoimmunity (T Cell Focus)
Future Antivirals Using Bacterial Immune Sensors
Base Editing of CAR-T Cells Clear Incurable Leukemia
Elevated Interleukin 6 (IL-6) and Normal C Reactive Protein (CRP)
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