Impella is a ventricular assist device, that is FDA approved for short-term support of the left ventricle. There is also a version that can be used for the right ventricle as well. The device can support 2.5 to 5 L/min of blood flow, the latter of which is considered...
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Physiology Lecture # 2 Study Notes: Properties of Pulmonary Vasculature
The heart pumps a volume of blood into the lungs which after getting oxygenated is transported back to heart. This oxygenated blood is then pumped out of the heart and into the aorta and subsequently into the systemic circulation. As a consequence, at any given time...
CVS Physiology Lecture # 18 Study Notes: Nodal Action Potential
NODAL ACTION POTENTIAL VS. VENTRICULAR ACTION POTENTIAL The nodal tissues and the Purkinje fibers exhibit automaticity in their properties as they are able to undergo spontaneous depolarizations. In other words, these tissues do not require the need of an external...
CVS Physiology Lecture # 11 Study Notes: Autoregulation – Nitric Oxide
Nitric Oxide is called an endothelium derived relaxing factor (EDRF) as it is released by the endothelium of the blood vessel. EDRF cause relaxation of the vascular smooth muscle, and as a result cause vasodilation of the blood vessel. The following factors contribute...
CVS Physiology Lecture # 20 Study Notes: Ventricular Action Potential
TYPES OF CHANNELS AND CONCENTRATIONS OF VARIOUS IONS Sodium Channels: The concentration of sodium ions outside the cell membrane is greater than that inside the cell. Therefore, there is a passive movement of sodium ions into the cell as the channels open. The sodium...
Physiology Lecture # 6 Study Notes: Hemodynamics – Vascular Resistance
Resistance can be integrated into two types of circuits; parallel and serial circuit. Series Circuit The heart is placed in series with the pulmonary vasculature and as well as the rest of the body. It pumps blood to the lungs, from where the blood travels back to the...
CVS Physiology Lecture # 8 Study Notes: Hemodynamics – Reynolds Number
Definition: Reynolds Number is used to predict the type of blood flow in a blood vessel. There are two types of blood flow: Click Here To Watch Video Lecture For This Topic Laminar Flow: The laminar flow is described as the flow of fluid which is travelling in a calm,...
Physiology Lecture # 6 Study Notes: Hemodynamics – Vascular Compliance
Capacitance is defined as the distensibilty of a blood vessel. In other words, capacitance is the ability of an object to get stretched. In contrast, elasticity is defined as the object's ability to recoil or return to its previous shape after being stretched....
Physiology Lecture # 5 Study Notes: Hemodynamics – Poiseuille’s Equation
The Poiseuille's Equation takes into account factors such as blood viscosity, length and cross sectional area of a blood vessel and uses it to determine the resistance to the flow of blood. R=8 n Lπr^4 (Assuming that the flow is laminar and the volume is constant)...
CVS Physiology Lecture # 12 Study Notes: Autoregulation – Muscle Blood Flow
The metabolic requirements of a muscle change during exercise compared to when it is at rest. The blood flow also changes accordingly with the metabolic demands of the muscle. Therefore, the purpose of this lecture is to establish a better understanding of the...